A Survey on the Computational Approaches to Identify Drug Targets in the Postgenomic Era

Chemical genomics as an emerging paradigm for postgenomic drug discovery.

Chemical genomics approaches are evolving to overcome key problems limiting the efficiency of drug discovery in the postgenomic era. Many of these stem from the low success rates in finding drugs for novel genomics targets whose biochemical properties and therapeutic relevance is poorly understood. The fundamental objective of chemical genomics is to find and optimize chemical compounds that ca...

RNAi technology: A Novel approaches against fungal infections

Despite the introduction of new antifungal agents, resistances to antifungal therapy continue to increase and outcome of invasive fungal infections treatment is frequently suboptimal. A large amount of the recent effort in antifungal drug discovery has focused on a limited set of targets with functions known or expected to be important for fungal viability and virulence. A variety of techniques...

Choosing anticancer drug targets in the postgenomic era.

Sports Result Prediction Based on Machine Learning and Computational Intelligence Approaches: A Survey

In the current world, sports produce considerable statistical information about each player, team, games, and seasons. Traditional sports science believed science to be owned by experts, coaches, team managers, and analyzers. However, sports organizations have recently realized the abundant science available in their data and sought to take advantage of that science through the use of data mini...

Newest Targets for Anticonvulsant Agents: An Overview

Epilepsy is a neurological condition characterized by recurrent seizures influencing about 1% of the worldwide population. Despite much progress in understanding the pathogenesis of epilepsy, the molecular basis of human epilepsy still remains unclear. Common approaches for pharmacotherapy of epilepsy are still directed towards controlling the symptoms and suppression of seizures. Clinical use ...